| Date | Location | Result | |
| Nov 11, 2000 | Vermillion, S.D. | South Dakota State 3, South Dakota 0 (15-9,15-12,15-7) | Box score |
| Nov 10, 2000 | Vermillion, S.D. | Augustana 3, South Dakota 0 (16-14,15-6,15-8) | Box score |
| Oct 31, 2000 | Mankato, Minn. | Minn St, Mankato 3, South Dakota 0 (15-8,15-11,15-13) | Box score |
| Oct 28, 2000 | Grand Forks, N.D. | North Dakota 3, South Dakota 1 (15-13,4-15,15-8,15-5) | Box score |
| Oct 27, 2000 | Fargo, N.D. | North Dakota State 3, South Dakota 0 (15-8,15-8,15-6) | Box score |
| Oct 24, 2000 | Sioux City, Iowa | Morningside 3, South Dakota 0 (14-3,15-6,18-16) | Box score |
| Oct 21, 2000 | Vermillion, S.D. | Northern Colorado 3, South Dakota 1 (15-10,15-10,11-15,15-5) | Box score |
| Oct 20, 2000 | Vermillion, S.D. | Nebraska-Omaha 3, South Dakota 0 (15-3,16-14,15-0) | Box score |
| Oct 14, 2000 | Sioux Falls, S.D. | Augustana 3, South Dakota 0 (15-4,15-6,16-14) | Box score |
| Oct 13, 2000 | Brookings, S.D. | South Dakota State 3, South Dakota 0 (15-8,15-9,15-5) | Box score |
| Oct 07, 2000 | Vermillion, S.D. | Minn St, Mankato 3, South Dakota 2 (13-15,15-5,6-15,15-12,15-5) | Box score |
| Oct 06, 2000 | Vermillion, S.D. | South Dakota 3, St. Cloud State 0 (15-9,16-14,15-11) | Box score |
| Sep 30, 2000 | St. Joseph, Mo. | Missouri Western St 3, South Dakota 0 (15-13,15-8,15-13) | Box score |
| Sep 30, 2000 | St. Joseph, Mo. | South Dakota 3, Southwest Baptist 1 (15-6,15-7,11-15,15-8) | Box score |
| Sep 29, 2000 | St. Joseph, Mo. | South Dakota 3, Hastings 2 (15-11,21-19,8-15,12-15,15-13) | Box score |
| Sep 29, 2000 | St. Joseph, Mo. | Rockhurst 3, South Dakota 1 (18-20,15-10,15-9,15-13) | Box score |
| Sep 26, 2000 | St. Cloud, Minn. | South Dakota 3, St. Cloud State 2 (15-12,12-15,17-15,7-15,15-7) | Box score |
| Sep 23, 2000 | Vermillion, S.D. | North Dakota State 3, South Dakota 0 (15-7,15-9,15-5) | Box score |
| Sep 22, 2000 | Vermillion, S.D. | North Dakota 3, South Dakota 1 (15-7,15-11,14-16,15-9) | Box score |
| Sep 20, 2000 | Vermillion, S.D. | Briar Cliff 3, South Dakota 2 (4-15,15-11,15-5,11-15,15-9) | Box score |
| Sep 16, 2000 | Omaha, Neb. | Nebraska-Omaha 3, South Dakota 1 (11-15,15-9,15-8,15-1) | Box score |
| Sep 15, 2000 | Greeley, Colo. | Northern Colorado 3, South Dakota 1 (9-15,15-9,15-11,15-10) | Box score |
| Sep 12, 2000 | Vermillion, S.D. | Morningside 3, South Dakota 2 (16-14,11-15,15-11,12-15,15-12) | Box score |
| Sep 09, 2000 | Rochester, Minn. | Minn St, Moorhead 3, South Dakota 0 (15-10,15-8,15-9) | Box score |
| Sep 08, 2000 | Rochester, Minn. | Northern State 3, South Dakota 2 (15-7,15-13,8-15,6-15,17-15) | Box score |
| Sep 08, 2000 | Rochester, Minn. | South Dakota 3, Minnesota-Crookston 0 (15-3,15-7,15-4) | Box score |
| Sep 02, 2000 | Sioux City, Iowa | Morningside 3, South Dakota 0 (15-2,15-12,15-3) | Box score |
| Sep 02, 2000 | Sioux City, Iowa | South Dakota 3, Wayne State 0 (15-10,15-3,15-11) | Box score |
| Sep 01, 2000 | Sioux City, Iowa | South Dakota 3, Winona State 0 (15-11,15-13,15-10) | Box score |
| Sep 01, 2000 | Sioux City, Iowa | Quincy 3, South Dakota 1 (13-15,15-5,15-13,17-15) | Box score |
| Aug 30, 2000 | Vermillion, S.D. | South Dakota 3, Wayne State 2 (9-15,10-15,15-11,15-7,17-15) | Box score |
| Aug 26, 2000 | Kearney, Neb. | South Dakota 3, Chadron State 0 (15-4,15-2,16-14) | Box score |
| Aug 26, 2000 | Kearney, Neb. | Findlay 3, South Dakota 0 (15-3,15-13,15-9) | Box score |
| Aug 25, 2000 | Kearney, Neb. | Nebraska-Kearney 3, South Dakota 0 (15-5,15-3,15-3) | Box score |
| Aug 25, 2000 | Kearney, Neb. | South Dakota 3, Tarleton State 0 (15-13,15-13,15-12) | Box score |