| Date | Location | Result | |
| 03/22/21 | San Antonio, Texas (Alamodome) | Oregon 67, South Dakota 47 | Box score |
| 03/09/21 | Sioux Falls, S.D. (Sanford Pentagon) | South Dakota 66, Omaha 43 | Box score |
| 03/08/21 | Sioux Falls, S.D. (Sanford Pentagon) | South Dakota 81, North Dakota St. 55 | Box score |
| 03/06/21 | Sioux Falls, S.D. (Sanford Pentagon) | South Dakota 89, Oral Roberts 66 | Box score |
| 02/28/21 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 81, North Dakota St. 61 | Box score |
| 02/27/21 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 82, North Dakota St. 81 | Box score |
| 02/21/21 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 76, Oral Roberts 54 | Box score |
| 02/20/21 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 77, Oral Roberts 54 | Box score |
| 02/14/21 | Grand Forks, N.D. (The Betty) | South Dakota 64, North Dakota 47 | Box score |
| 02/13/21 | Grand Forks, N.D. (The Betty) | South Dakota 72, North Dakota 63 | Box score |
| 02/06/21 | Brookings, S.D. (Frost Arena) | South Dakota St. 80, South Dakota 75 | Box score |
| 02/05/21 | Brookings, S.D. (Frost Arena) | South Dakota St. 64, South Dakota 45 | Box score |
| 01/23/21 | Macomb, Ill. (Western Hall) | South Dakota 61, Western Ill. 56 | Box score |
| 01/22/21 | Macomb, Ill. (Western Hall) | South Dakota 73, Western Ill. 56 | Box score |
| 01/09/21 | Kansas City, Mo. (Swinney Center) | South Dakota 80, Kansas City 53 | Box score |
| 01/08/21 | Kansas City, Mo. (Swinney Center) | South Dakota 92, Kansas City 34 | Box score |
| 01/03/21 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 89, Denver 74 | Box score |
| 01/02/21 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 87, Denver 47 | Box score |
| 12/30/20 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 89, Midland 39 | Box score |
| 12/20/20 | Norman, Okla. (Lloyd Noble Center) | Oklahoma 80, South Dakota 73 | Box score |
| 12/17/20 | Peoria, Ill. (Renaissance Coliseum) | South Dakota 84, Bradley 68 | Box score |
| 12/10/20 | Wichita, Kan. (Charles Koch Arena) | South Dakota 62, Wichita St. 54 | Box score |
| 12/06/20 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 89, Lipscomb 52 | Box score |
| 11/30/20 | Sioux Falls, S.D. (Sanford Pentagon) | Gonzaga 54, South Dakota 50 | Box score |
| 11/28/20 | Sioux Falls, S.D. (Sanford Pentagon) | South Carolina 81, South Dakota 71 | Box score |